HY peptides modulate transplantation responses to skin allografts
نویسندگان
چکیده
منابع مشابه
HY peptides modulate transplantation responses to skin allografts.
Injection of female C57BL/6 mice with immature female bone marrow-derived dendritic cells (BMDC) pulsed with a single immunodominant HY(Db) Uty peptide, WMHHNMDLI, induces prolonged survival of syngeneic male skin grafts. In contrast, injection of immature female BMDC pulsed with a single MHC class I-restricted HY(Ab) Dby peptide, NAGFNSNRANSSRSS, causes immunization similar to that following i...
متن کاملTransplantation tolerance induced by intranasal administration of HY peptides.
Induction of antigen-specific tolerance to transplantation antigens is desirable to control host-versus-graft and graft-versus-host reactions. Following molecular identification of a set of minor histocompatibility (H) antigens, we have used selected HY peptide epitopes for this purpose. Intranasal administration of individual major histocompatibility complex (MHC) class II-restricted HY peptid...
متن کامل[The clinical use of cryopreserved human skin allografts for transplantation].
BACKGROUND The biological recovery of human skin allografts is the gold standard for preservation in Skin Banks. However, there is no worldwide consensus about specific allocation criteria for preserved human skin allografts with living cells. A report is presented on the results of 5 years of experience of using human skin allografts in burned patient in the Skin and Tissue Bank at the "Instit...
متن کاملA shortcut to peptides to modulate platelets.
There has been something of a quiet revolution occurring in biology related to a growing realization of the functional importance of sequences within irregular parts of biomolecules. For instance, it is now clear that ‘junk DNA’ is nothing of the kind: non-coding DNA and RNA are now known to play critical roles in all manner of biological processes1. It is also increasingly clear that disordere...
متن کاملMicrovascular transplantation of physeal allografts.
We compared growth in vascularised allograft transplants, autografts and in non-operated physes in rabbits immunosuppressed with cyclosporin A and in non-immunosuppressed animals. Molecular haplotyping was undertaken before operation to ensure allogenicity. Postoperative bone scans and fluorochrome labelling were used to confirm physeal vascularity. The animals were killed at three or five week...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Immunology
سال: 2002
ISSN: 1460-2377
DOI: 10.1093/intimm/dxf093